I study the healthy brain through non-invasive multimodal neuroimaging techniques to uncover the complex relationships among its anatomical, functional, metabolic, and molecular characteristics. I am currently Senior Scientist in the Neuroenergetics Lab at the Institute of Neuroradiology from Uniklinikum Erlangen and Medical Imaging Scientific Consultant in the Biosciences group of SURA.
🔥 News
- 2025.07: ✨ I was invited to present our work on Quantitative metabolic brain imaging using simultaneous PET/MRI at DACH-ISMRM Workshop Munich 2025
- 2024.08: ✨ Comprehensive CEST of HC accepted as oral presentation at ESMRMB Barcelona 2024
- 2024.07: ✨ The molecular fingerprint of CEST accepted as oral presentation at CEST workshop Nürnberg 2024
- 2024.04: ✨ The energetic costs as a proxy of cognition accepted as oral presentation at OHBM Seoul 2024
- 2024.03: 🥉 Third place ECCN Leipzig 2024
- 2024.02: ✨ The energetic costs as a proxy of cognition accepted as oral presentation at ECCN Leipzig 2024
- 2023.12: ✨ My Postdoctoral project “the energetic costs of signaling” just got published in Science Advances
📝 Selected Publications
An energy costly architecture of neuromodulators for human brain evolution and cognition
Gabriel Castrillon, Samira Epp, Antonia Bose, Laura Fraticelli, Andre Hechler, Roman Belenya, Andreas Ranft, Igor Yakushev, Lukas Utz, Lalith Sundar, Josef P Rauschecker, Christine Preibisch, Katarzyna Kurcyus, Valentin Riedl
I audited where all the sugar is spent in the 🧠, generating a map of the energetic costs, interpreted from evolutive, cytoarchitectural, molecular, and cognitive points of view.
Antonia Bose & Samira Epp, Roman Belenya, Katarzyna Kurcyus, Eric Ceballos Dominguez, Andreas Ranft, Eliana Salas Villa, Moritz Bursche, Christine Preibisch, Gabriel Castrillon & Valentin Riedl
We simultaneously measured CMRO2 and CMRglc for the first time, showing an increase in glucose metabolism without a corresponding rise in oxygen consumption, which suggests an enhanced glycolytic metabolism during brain activity.
The control costs of human brain dynamics
Eric Ceballos Dominguez, Andrea I. Luppi, Gabriel Castrillon, Manish Saggar, Bratislav Misic, Valentin Riedl
Eric showed that the brain balances functional efficiency and energy conservation by minimizing costly transitions between different activity states using network control theory.